Cortland Police say they responded to an assault call near the corner of Main Street and Groton Ave at about 2:15 this morning, where 28-year-old Damian Grant of Cortland had been stabbed in his upper body area.
Nearby TLC personnel transported him to Cortland Regional Medical Center, where he was later pronounced dead from his injuries.
Police have identified the suspect as 32-year-old Andrew Pilcher, also of Cortland, and have charged him with manslaughter.
The cause of the incident is still under investigation, though Police believe the two men did not know each other prior to the altercation.
Cortland City Police were assisted at the scene by the New York State Police major crimes unit.